SuperSix EVO and CAAD13
Road BikeBest for: riders who want a lower race position
Current SuperSix EVO frames use 44, 48, 51, 54, 56, 58 and 61. CAAD13 uses a similar numeric system, but its available endpoints and geometry can vary by year.
Fit tip: If two sizes fit, compare stack and reach rather than choosing the larger number for comfort. A different cockpit setup is usually a better adjustment than an oversized race frame.
Synapse
Road BikeBest for: endurance riders who want a taller, less aggressive front end
Synapse uses numeric road labels from 44 to 61, but its endurance geometry is taller than the SuperSix EVO at a comparable size.
Fit tip: Start with the published Synapse height range. Do not size up just to raise the bars; compare stack and available spacer adjustment first.
Topstone and Topstone Carbon
Gravel BikeBest for: mixed-surface, endurance and bikepacking riders
Topstone uses XS to XL with deliberately broad overlaps. Cannondale's own guidance says height, leg length, flexibility and the planned riding style all matter.
Fit tip: Between sizes, a shorter torso usually favors the smaller frame. A longer torso can suit the larger one, provided you still have 2.5 to 5 cm of standover clearance.
Trail, Habit, Scalpel, and Jekyll
Mountain BikeBest for: cross-country, trail and enduro riders choosing by handling preference
These families use letter sizes, but their height bands differ. Trail starts smaller than Jekyll, while Habit and Scalpel have broad overlaps through the middle sizes.
Fit tip: Use the smaller overlapping size for easier direction changes and the larger one for a roomier cockpit, after confirming standover and dropper-post insertion.
Quick, Adventure, and Treadwell
Hybrid BikeBest for: fitness, commuting and upright recreational riding
Quick has the widest letter-size run. Adventure and Treadwell use fewer, broader sizes, and Remixte or low-step versions may not offer the same labels as diamond frames.
Fit tip: A low-step frame improves mounting clearance but does not shorten the cockpit automatically. Choose by comfortable reach and saddle adjustment.
Moterra, Adventure Neo, Tesoro Neo, and Treadwell Neo
E-BikeBest for: electric mountain, commuting and trekking riders
Cannondale e-bike families do not share one size run. Moterra commonly uses S to XL, while some urban and compact models use fewer sizes or one-size geometry.
Fit tip: Check the exact e-bike frame style and model chart. When two sizes fit, favor the option you can balance, mount and handle confidently at low speed.